Over/Under 2.5 goals
Italy have only been knocked out at the quarter-finals of a major tournament on two of the nine occasions that they have reached this stage - both times on penalty kicks (Euro 2008 v Spain and World Cup 1998 v France).
In 10 quarter-final matches at the European Championship or World Cup (including one replay), Italy have conceded only four goals - and never more than one in a game.
England have lost seven out of ten quarter-final games at major tournaments, with 1966, 1990 and 1996 the only exceptions.
England and Italy have met at the European Championship once before, with Italy winning a group game 1-0 in 1980.
The last clash between the nations saw England lose a friendly in Leeds 2-1 in March 2002.
England have managed just one win from their last nine games against Italy (D2, L6).
On the last occasion that England qualified for a European Championship (2004), the Three Lions exited at the quarter-final stage after losing a penalty shoot-out against hosts Portugal.
Italy, too, exited at the quarter-final stage last time around. In 2008, they held Spain to a goalless draw before losing the penalty shoot-out.
England had the best shot conversion rate in the group stages (21.7%).
Italy and England scored three goals each from set-pieces, the joint-most in the group stages of Euro 2012.
Both Italy and England scored the opening goal in each of their first three games, with Germany the only other team to have managed to do so.
Italy's Mario Balotelli will play against his Manchester City team-mates Joe Hart, Joleon Lescott and James Milner.
England manager Roy Hodgson managed Italian sides Inter (1995-97 and 99) and Udinese (2001) and led Inter to the final of the 1996/97 UEFA Cup (where they were defeated by Schalke on penalties).
The Azzurri remain unbeaten in competitive games under Cesare Prandelli: 13 games, nine wins and four draws.