Can the Bills slow down Miami's offence?
Miami blew the roof off the NFL with a 70-point bonanza last week to become one of just three teams to remain unbeaten after another epic weekend of NFL action.
This week sees more of the same, with some must-win games, teams trying to save their own season and also the start of the annual pilgrimage across the Atlantic as Wembley hosts the first of three more London games.
So there's plenty of excitement for week four in the NFL....
NFL Week Four Sunday
Atlanta Falcons (2-1) @ Jacksonville Jaguars (1-2)
Match Odds: 5/42.25 | 13/20
Spread: Jaguars -3
The Jaguars hope their two-week stand in their second home of London can spark some form after a disappointing start to a season they hoped would bring big things.
It'd help if Travor Lawrence hadn't seen nine of his passes dropped already, and losing at home to the Texans last week is now something of a tradition (lost six in a row at home v Houston) but in London they could bounce back.
Atlanta failed to score a touchdown last week as the Lions put everything into stopping rookie rusher Bijan Robinson and put the onus on Desmind Ridder - it worked.
The Jags have a defensive front that could do exactly the same and that combined with Lawrence's receivers making a few more plays should result in them getting a Wembley win.
Miami Dolphins (3-0) @ Buffalo Bills (2-1)
Match Odds: 5/42.25 | 7/101.70
Spread: Bills -3
The 3-0 Dolphins are three-point underdogs despite obliterating the Broncos by scoring 70 (seventy) points - that's more than 18 teams have managed all season!
The Dolphins are averaging 550 yards per game and although this Bills team will be their biggest test it's hard to see them slowing Miami down totally, so their best bet is to hog the ball and let Josh Allen try and keep pace with early MVP candidate Tua Tagovailoa.
All three games last season between these two were sttled by three points or less, so giving this super-charged Miami offence a three-point head start looks like a gift.
Cincinnati Bengals (1-2) @ Tennessee Titans (2-1)
Match Odds: 7/101.70 | 6/52.20
Spread: Bengals -2.5
Both of these are stuttering on offence, ranking in the bottom five for both yards and points - while on defence they're allowing exactly the same 22.3 points per game!
The Bengals are doing a better job at keeping Joe Burrow upright, but his calf problem has been limiting his production. The Titans allowing the fifth-most passing yards is also a point in Cincy's favour.
So in a tight game between two evenly-matched struggling teams, give me the one true star on showm even with a dodgy leg.
Denver Broncos (0-3) @ Chicago Bears (0-3)
Match Odds: 8/131.61 | 11/82.38
Spread: Broncos -3.5
These two winless sides lost by a combined 81 points last week as they were both clobbered, so at least one should rebound this week. Chicago have the league's longest losing streak at 13 and it's been a year since Bears fans celebrated a win.
Justin Fields has the worst QB rating in the league but Russell Wilson has at least mustered some yards and points, so we'll back them to continue Chicago's long losing run.
Minnesota Vikings (0-3) @ Carolina Panthers (0-3)
Match Odds: 1/21.50 | 17/102.70
Spread: Vikings -4.5
Another game between two winless sides but the Vikings have been closing, losing all three by just 3, 6 and 4 points - and all this coming after a record 11 one-score wins last season!
Kirk Cousins leads the NFL in passing yards and the Vikings offence is second overall, so even with rookie Bryce Young back the Panthers will struggle to keep pace in this one.
Washington Commanders (2-1) @ Philadelphia Eagles (3-0)
Match Odds: 16/54.20 | 1/41.25
Spread: Eagles -8.5
Washington are the only team to beat Jalen Hurts in 21 regular season games, but the numbers don't stack up well this time - with the Eagles being able to dominate in the trenches on both sides of the ball.
Sam Howell has been sacked a league-high 19 times and has the second-most interceptions - and making sacks and grabbing picks are two things this Eagles defence does better than almost anyone.
Arizona Cardinals (1-2) @ San Francisco 49ers (3-0)
Match Odds: [11/2 | 1/91.11
Spread: 49ers - 14
Arizona's huge upset win over Dallas last week could actually be good for San Francisco to avoid complacency - and they look a more well-rounded team than the Cowboys.
Amazingly they've scored 30 points exactly in all three games so far and Arizona will make this closer than the odds suggest thanks to Josh Dobbs producing eye-catching displays and the Cards' run game.
But two upset wins against NFC giants in a row is too much to ask.
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Thursday Night Football
Detroit Lions (2-1) @ Green Bay Packers (2-1)
Match Odds: 17/20 | 1/12.00
Spread: Lions -1.5
Green Bay aren't talking revenge, but it'll definitely be on their minds as the Lions ended the Packers' playoff hopes, and Aaron Rodgers' career at Lambeau on their last visit last season.
Detroit have also won the last three meetings and come with an offence that's seen off the champion Chiefs already, and has scored 20 points or more in 12 straight games.
And for all the attention on Jordan Love and his young receivers, it'll be the Packers' D, which has held seven of their last eight opponents to 20 points or less, that will need to step up.
Injuries could really hurt Green Bay though, especially on the offensive line and especially after Detroit's seven-sack game in their commading win over Atlanta - a team that ran all over Green Bay in a tight win the week before.
If the Packers are at full health it may be a different story but the Lions just have a few too many factors in their favour being healthier, having won in primetime already this season and just looking a bit further ahead in their development. They're in good shape to pinch a close one and stun Lambeau again.