Manchester United v Southampton
Sunday 16:00, Sky Sports 1.
Match Odds: Manchester United 1.855/6, Southampton 4.84/1, The Draw 3.9.
December's meeting between Louis van Gaal and Ronald Koeman - two Dutch managers who have fallen out dramatically in the past - was an interesting tactical battle.
Koeman's Southampton dominated the game, Van Gaal's Manchester United only managed three shots, and yet it was United who won 2-1. Despite winning, it will be Van Gaal who might change his approach for the return game, with Koeman likely to ask for more of the same.
Van Gaal's injury problems in the centre of defence appear to be clearing up, and he could field Phil Jones, Chris Smalling and Jonny Evans in tandem for only the second time this season, after the trio played together at Stoke on New Year's Day. They should be capable of marshalling Graziano Pelle perfectly well - the Italian tends to drop deep towards play, and United will need to concentrate on picking up the midfield runners getting beyond him.
Van Gaal's problem is now in the wing-back positions. Rafael da Silva, Ashley Young and Marcos Rojo are all out, and Luke Shaw, Daley Blind and Antonio Valencia are considered doubtful. Therefore, it's extremely difficult to know which players will start here - it could be Shaw and Valencia, two defensively aware players, or it could be Adnan Januzaj and perhaps Angel Di Maria, who will concentrate more on attacking.
The positioning of United's wing-backs could be the game's key feature. In the reverse meeting, United allowed Southampton's wide midfielders to go free, and they found pockets of space between the lines to create good situations.
Here at Old Trafford, James Ward-Prowse and Dusan Tadic are likely to play the wide roles, and the latter could be a huge danger by cutting inside from the left and controlling the play. Michael Carrick, United's deep-lying midfielder, will have a big responsibility in terms of shutting down that space.
Central midfield is the area where Southampton might feel they can outmuscle Manchester United. Steven Davis will play at the top of the triangle and break forward to combine with Tadic and Pelle, while Morgan Schneiderlin and Victor Wanyama will sit deeper and attempt to put Southampton in command of the game.
United's combination in midfield will probably involve two of Wayne Rooney, Juan Mata and Angel Di Maria, so it will be about physical power versus technical quality. Di Maria's long-awaited return could transform United in the centre of the pitch, however, and make them more direct and purposeful in possession.
Alternatively, Rooney could be moved up the pitch into a centre-forward position alongside Robin van Persie. Radamel Falcao has now managed a few goals, but still doesn't look entirely sharp, and Van Gaal might consider that Rooney dropping deep from the centre-forward position would cause Southampton more problems.
Southampton have an excellent defensive record, and concede fewer shots than any other side in the Premier League because of their high defensive line, keeping the opposition away from goal. Any balls in behind them can be problematic, though, and Van Persie has become very good at prowling the channels and shooting from narrow angles. He scored both goals in the reverse fixture, and is understandably favourite to open the scoring again here.
The market suggests United are odds-on favourites, and considering their unbeaten - if slightly unconvincing - 10-game Premier League run, it's hard to disagree.
Nevertheless, I think Southampton will put up a good fight, and Van Gaal might require a substitute or a formation switch in order for United to press home their advantage. I'll back Draw / Manchester United in Half-Time / Full-Time at 5.49/2.
Recommended Bet
Back Draw/Man Utd in Half-Time/Full-Time @ 5.49/2