Manchester United v Tottenham
Monday 20:00, Sky Sports Main Event
Match Odds: Manchester United 2.68/5, Tottenham 3.185/40, The Draw 3.412/5.
Manchester United have won each of their last home fixtures against Tottenham Hotspur, keeping a clean sheet every time - but after last weekend's shocking defensive display in a 3-2 defeat at Brighton, it would be something of a surprise if that run continued here.
Mourinho likely to make defensive changes
The performances of both Victor Lindelof and, in particular, Eric Bailly were so catastrophic that it would be a major surprise if Jose Mourinho didn't make changes here.
Marcos Rojo is out, but Phil Jones and Chris Smalling will both fancy their chances of a return. In fact, it's not impossible that Mourinho will switch to a three-man defence, as he's done against Tottenham in previous encounters.
Either way we're also likely to see the return of Antonio Valencia on the right of defence, which could mean Ashley Young switching sides and playing on the left, as Luke Shaw has been questionable defensively so far this season.
Nemanja Matic is another set to come into the side in the deep midfield role. This could mean Fred dropping out after a poor display at Brighton, with Paul Pogba pushed higher in the midfield triangle - if there are three central midfielders deployed.
In the final third, Romelu Lukaku appears the only surefire starter. On the left, Alexis Sanchez's fitness is still in doubt, Anthony Martial was another poor performer at Brighton and therefore Marcus Rashford may come into the side.
On the right, Juan Mata was replaced by Jesse Lingard at half-time last weekend and Mourinho might prefer to use the Englishman from the start, with his tactical discipline being useful against a well-organised, compact Spurs side.
Will Spurs use a back three?
Mauricio Pochettino used a three-man defence for the 3-1 victory over Fulham last weekend, with Davinson Sanchez playing between Jan Vertonghen and the returning Toby Alderweireld.
That seems likely to be Spurs' approach again here, with a high defensive line pushing United back into their own half. It might expose them to the speed of Lukaku, but Pochettino will be confident that Sanchez boast enough pace to cope.
Kieran Trippier and Ben Davies would play as wing-backs, although there would be a question mark about the composition of the midfield. Last weekend Pochettino used Eric Dier as the sole holding midfielder behind Christian Eriksen and Deli Alli, although here he might summon Mousa Dembele, who often performs well against Manchester United, for some extra muscle in midfield.
That could push Eriksen and Alli into higher positions, supporting Harry Kane more closely. Lucas Moura scored a fine curling strike against Fulham but could be the man to drop out here.
But overall, this seems a very uncertain tactical battle: both managers could name a back three or a back four, with various question marks about personnel in attacking positions.
The key battle seems to be Lukaku up against Tottenham's centre-backs, including two of his international teammates. Lukaku's movement has been good so far this season, and he's likely to make runs into the inside-right channel up against Vertonghen. Spurs must put pressure on the ball to play a high line against Lukaku.
The battle down the flanks could be intriguing, too. Trippier is a constant threat with his right-wing delivery, and neither Shaw nor Young have performed well so far this season. On the other side, the return of Valencia could be crucial for United, as he's a better all-round player than Davies, who often looks somewhat ponderous at wing-back.
I can't shake the feeling that Tottenham will come away from Old Trafford with something. They're a better organised side, better at transitions and are more comfortable than United at switching between systems.
United have been hugely underwhelming so far this season, and I think they're underpriced here. I'll lay Manchester United at 2.68/5.