Manchester City v Tottenham
Saturday 12:30, Sky Sports Premier League
Match Odds: Man City 1.330/100, Tottenham 12.011/1, The Draw 6.86/1
Just three days after an absolutely ludicrous Champions League second leg which featured seven goals and a last-minute eighth disallowed, Tottenham Hotspur are back at the Etihad for Saturday lunchtime kick-off.
Fatigue will play a big role
After such an intense and draining encounter, it's difficult to imagine that either side will be particularly fresh for this game, and you have to think the minimal turnaround time benefits Manchester City, the side with far more capacity to rotate. Pep Guardiola has been accused of overthinking the Champions League tie and meddling too much with his starting XI, but if he does the same thing again this time around, it will be about fitness rather than tactics.
It seems likely that John Stones will return in defence, with Danilo or Fabian Delph likely to start on the left with Benjamin Mendy probably not being risked for a second game. Kyle Walker and Aymeric Laporte are more likely to retain their places, with Ederson continuing in goal.
De Bruyne likely to continue
Fernandinho was only used in the second half on Wednesday night and could return in place of Ilkay Gundogan, or alternatively it could be David Silva - perhaps feeling the effects of a long season - dropping out, and Gundogan moving forward, or Bernardo Silva coming inside from the flank to play his preferred central midfield role. Kevin De Bruyne, outstanding in the second half, will surely continue.
In the final third, it would be a huge surprise if Leroy Sane doesn't return on the left flank, with Raheem Sterling - nearly the hero in midweek - probably reverting to the right. Gabriel Jesus could replace Sergio Aguero, who doesn't look right after his recent injury problem, and could do with a rest.
Pochettino to switch system?
Tottenham have serious injury problems. Serge Aurier, Harry Winks and Harry Kane were already out of contention, and there is now a serious doubt about Moussa Sissoko, who limped off in the first half. Eric Dier and Erik Lamela seem unlikely to be available either.
But Mauricio Pochettino must surely rotate. The availability of both Davinson Sanchez and Juan Foyth means Pochettino could switch to a three-man defence, simply because he needs to play eleven fit players in a proper system, rather than because the move makes sense tactically.
In midfield, Spurs are struggling for numbers if Sissoko is out. It would be a surprise if Victor Wanyama is selected for another game so quickly, so Christian Eriksen and Dele Alli may have to play deeper roles, perhaps supported by youngster Oliver Skipp.
Son and Lucas to lead the attack?
Going forward, the introduction of Fernando Llorente eventually proved crucial in Spurs' midweek triumph, but the Spaniard slowed Spurs' play and denied them counter-attacking chances. He's another who probably won't be able to manage 90 minutes, so it makes more sense to use Lucas Moura and Son Heung-min as a purely counter-attacking front two, making runs into the channels.
It's difficult to escape the feeling that this will be a slow-burning game. The tremendous ferocity with which the game in midweek started surely won't be possible with both sides somewhere between 'exhausted' and 'rotated'.
It also feels inevitable that Manchester City will benefit from the unusual nature of the fixture. Ultimately, Guardiola is able to bring in fresh attackers like Sane and Jesus, whereas Pochettino is almost forced into considering using Llorente from the start here.
This game will probably be about freshness rather than tactics - and, perhaps, the fact that City want revenge and know dropping points here could be fatal for their title hopes, while for Spurs the game is less decisive. I'll back Man City / Man City at 1.910/11 in the Half-Time / Full-Time market.