Chelsea's lead at the top of the Premier League table is now just four points following a 2-0 defeat at Manchester United on Sunday afternoon, 24 hours after Tottenham's impressive 4-0 win over Bournemouth.
After the Lilywhites had applied the pressure with their victory over the Cherries on Saturday - making it seven league wins on the spin for Mauricio Pochettino's men - all eyes were on Old Trafford to see if Chelsea could pass their latest test against their old boss Jose Mourinho.
But it was United who started much the brighter and went ahead in just the eighth minute when Marcus Rashford beat the offside trap to collect a superb through ball from Ander Herrera before tucking the ball home.
Antonio Conte's men surprisingly looked ruffled, and failed to register a single shot on target during a poor first half display in which Diego Costa looked more intent on squaring up to Marcos Rojo then he did on putting the ball in the back of the net.
And Chelsea's lacklustre performance was duly punished just minutes into the second half when Herrera's shot took a deflection off Kurt Zouma before passing the stranded Asmir Begovic.
The 2-0 scoreline was no more than United deserved, and although they conceded loads of possession late on they never looked in any danger of relinquishing their advantage, Conte's men amazingly still failing to record a single shot on target as the final whistle blew.
Chelsea, who just weeks ago held a 10-point lead over Tottenham and traded at just [1.03] to win the Premier League title, are now out to [1.2] with Spurs trading at [6.2].
Southampton (H) - 25 Apr
Everton (A) - 30 Apr
Middlesbrough (H) - 8 May
West Brom (A) - 12 May
Watford (H) - 15 May
Sunderland (H) 21 May
Crystal Palace (A) - 26 Apr
Arsenal (H) - 30 Apr
West Ham (A) - 5 May
Man United (H) - 15 May
Leicester (A) - 18 May
Hull (A) - 21 May