Southampton may have lost several stars to Liverpool this summer but they go into this game ahead of them in the Premier League. Opta provides the statistical analysis.
"Liverpool are unbeaten in their last nine Barclays Premier League matches (W6 D3)."
Saints have allowed their opponents just 66 shots on target this season, fewer than any other Premier League side. Southampton are 11/53.2 to keep a clean sheet.
Liverpool have had 14 different scorers in the Premier League this season, the joint-most along with Arsenal. Over 2.5 goals is 6/52.2.
Raheem Sterling has scored in both of his last two Premier League games against Southampton. Sterling is 12/53.4 to find the net.
Liverpool are unbeaten in their last nine Barclays Premier League matches (W6 D3). They are 85/403.1 to win.
Liverpool have now scored 101 Premier League penalties, more than any other side. Mario Balotelli is 11/53.2 to score.
Brendan Rodgers' side have shipped 62% of their goals in the second-half, the highest proportion in the top flight. The Liverpool half-time/draw full-time double result is 16/117.0.
Southampton have won only one of their last seven home Barclays Premier League matches where the opposition has scored. Liverpool are 9/25.7 to win half-time/full-time.
Following five successive wins, Southampton have won just two of their last seven Premier League home matches (W2 D2 L3). The draw is 12/53.4.
Jose Fonte has made more interceptions than any other player in the Premier League this season (71). Under 2.5 goals is 4/51.79.
Graziano Pelle has fired in the most shots of any Premier League player this season (73, excluding blocked shots). Pelle is 2/13.0 to score.