Crystal Palace have won just two of their 16 Premier League matches against Southampton, (D4 L10). The draw is 3.39/4.
Southampton have lost their last two Premier League trips to Selhurst Park to face the Eagles, this after avoiding defeat in their first six there (W3 D3). Crystal Palace are 3.185/40 to win.
Saints have won three of their last four meetings with Crystal Palace in all competitions, losing the other. Southampton are 2.6213/8 to win.
The new Palace manager Roy Hodgson (70 years old) is only the third manager to take charge of a Premier League game in his 70's after Sir Alex Ferguson and Bobby Robson. Hodgson is 1.68/13 to avoid defeat in the Double Chance market.
Should Crystal Palace lose and fail to score in this game, they'll be the first top-flight side in history to open a season with five defeats and no goals. Southampton are 4.05 to win to nil.
Crystal Palace's xG (expected goals) figure in the Premier League this season is 4.73 - suggesting that an average team would have scored five goals from the chances they've had. This xG tally is higher than Chelsea's (4.08), who have scored eight goals. Over 2.5 goals is 2.3211/8.
The Premier League record for longest time taken by a team to score a goal in a season is 438 minutes, held by Newcastle United in 2005-06. If Crystal Palace don't score before the 78th minute in this match, they'll break this record. Under 2.5 goals is 1.75/7.
Southampton have failed to score in nine of their last 12 Premier League matches, including three of their four games so far in 2017-18. Under 1.5 goals is 3.052/1.
No Southampton player has scored more goals for the club in the Premier League since the start of 2016-17 than Charlie Austin (7 - level with Nathan Redmond), despite the striker only playing 989 minutes in this period (a goal every 141 mins on average). Austin is 3.02/1 to find the net.
Christian Benteke has scored five goals in his last five Premier League appearances against Southampton, including three in two for Crystal Palace. Benteke is 2.85 to score.