"The Brendan Rodgers' derby" - which was how this match was described on our Football... Only Bettor podcast this week - gets Saturday's action underway at 12:30.
Andy Schooler says: ""Nine of Watford's 14 home games have been level at the interval and Leicester have been one of the best second-half teams this season."
Back Draw/Leicester HT/FT @ 5.95/1
At 3pm on Saturday Arsenal aim to bounce back from their midweek defeat with a tricky trip to Brighton.
Dave Tindall says: "I'm a fan of both teams to score here and, full disclosure, for now I'm going to pursue a strategy of backing away teams in my Premier League previews."
Back Arsenal to win and BTTS at 4.47/2
West Ham restart their troubled season at 17:30 with a home match against a Wolves side with plenty to feel positive about.
Steve Rawlings says: "Wolves are unbeaten in their last nine Premier League matches in the capital and they'll be confident of making it ten..."
Back Wolves @ 2.265/4
Saturday's action concludes from 19:45 as one of the top flights most promising young managers pits his wits against one of its most experienced.
Dan Fitch says: "Crystal Palace come into this match off the back of three consecutive clean sheets."
Back the draw at 3.39/4
Norwich and Southampton get things underway on Friday night at Carrow Road, with plenty at stake for the hosts as they begin an unlikely relegation survival bid.
Simon Mail says: "Six of Southampton's ten league wins have come away from home and it would be no surprise if they added to this record at Carrow Road."
Back Southampton @ 5/4 (Sportsbook)
What a match-up this is for Friday night, as Jose Mourinho manages Tottenham against former club Manchester United.
Mark O'Haire says: "The mini pre-season should also have allowed Mourinho the time to implement key ideas, team shape and defensive structure."
Back Tottenham Double Chance and Under 3.5 Goals at 2.1011/10 in Tottenham v Manchester United
We'll be publishing previews for all of Sunday's matches on Saturday morning so check back to find out where our experts are putting their money.