The Championship is our first stop on this journey through the English lower divisions - and Brentford welcome Wolverhampton Wanderers to Griffin Park, desperate to cement their position in the top six.
Mark Warburton's hosts currently find themselves in fifth position following an impressive start to the campaign, and will be keen to make the most of their home advantage here.
A 2-1 local derby win against Fulham last weekend was the fourth victory in a row for the Bees - and it's not just the points, but the manner and impact of those results which is most eye-catching.
The Bees have beaten Leeds United, Reading, Derby County, Notts Forest and Millwall in recent weeks, so the name of Wolverhampton Wanderers certainly won't scare them.
And five wins and a draw from their last seven on their own patch indicates that the hosts are more than capable of grinding out three points here.
Visitors Wolves make this trip south having lost their last three, and 10 goals shipped in that time, alongside just one scored at the other end, underlines just how bad they've been.
In fact, Kenny Jackett's side have won just one of their last seven away from Molineux, and in the bigger picture, 15 goals conceded in half a dozen outings points to serious issues in their backline.
All of this leaves the Midlands club sitting 11th in the second tier - and incredibly, just three points from the play-offs.
But I reckon momentum counts for a lot. That's something that Brentford have in abundance - and Wolves are severely lacking.
Bet 1: Brentford (HOME) @ 2.35/4
Dropping a division now, to League One, as MK Dons line up on their own turf against struggling Colchester United.
The home side go into this encounter in fourth position, three points off third, and will fancy their chances of pulling off a victory here.
It's now four games unbeaten for Karl Robinson's side, consisting three wins and a draw, and nine goals notched in that time suggests that they have no problems putting opponents to the sword at stadium:mk.
Visitors Colchester United are languishing in 21st place ahead of kick off - that's the final relegation spot, and although they're just a point off safety, recent results indicate that they have a long way to go yet.
Tony Humes' charges have managed just a single league win from seven, and are without victory in four on the road - six hours of football where they've shipped a whopping 10 goals.
A 1-0 loss at home to fellow strugglers Coventry City last week will have knocked confidence down at the Weston Homes Community Stadium, and it's now 10 games since the visitors managed a clean sheet.
In fact, the Dons are unbeaten in eight home league meetings with their guests - and I can't see that changing today.
Bet 2: MK Dons (HOME) @ 1.618/13
And finally, we're heading to League Two, as third-placed Luton Town welcome Mansfield Town to Bedfordshire.
The home side dropped points last week, losing to Burton Albion, and that has seen them fall to third place in the fourth tier.
But let's put things into perspective - that's their first loss in eight games, the other seven of which have seen six wins and a draw.
And their form on their own patch is strong. Five straight wins, 11 goals and three cleans sheets in that time leaving them full of confidence and cutting edge as we stand on the brink of December.
Indeed, a win for John Still's side today could quite easily lift them back into top spot - with just a point separating them from leaders Wycombe Wanderers before kick off.
Visitors Mansfield, meanwhile, don't have quite so much to boast about.
The Stags line up in 17th position, and that is largely due to a league run which has produced a single win from nine attempts.
Paul Cox will be keen for his charges to build on that defeat of Plymouth Argyle last weekend, though half a dozen without a win on the road indicates that it won't be easy for the Nottinghamshire club.
The last time these two sides met in League Two, Luton ran out 5-3 winners. My money's on them to nick the points again - and they're decent value considering, too.
Bet 3: Luton Town (HOME) @ 1.9520/21
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