The value hunters have been nibbling at Bournemouth all week - moving Eddie Howe's team in from 11.521/2 to 9.08/1 - let's join them.
It's speculative but backing 8-1 shots is generally speaking just that, so let's outline why they might upset the odds...
Liverpool's thin squad is feeling the strain of a tough season and a few notable first team players are out. Even if Brendan Rodgers picks the strongest team available to him the Merseyside outfit are vulnerable. No Luis Suarez - who didn't start in the third round remember - and they are really vulnerable.
And surprise results do happen. It was just about a year ago that Liverpool, including Suarez, lost at League One's Oldham, a result backed at 18.5 on Betfair.
The two teams have met twice in the FA Cup and Bournemouth forced a replay on both occasions, so they only have to go one better (yes, we'll overlook the fact that those games took place in 1968 and 1927!)
It would be a massive shock were the Premier League's fourth ranked side to lose but the cup is all about upsets as Oldham proved last year.
From one seaside town to another, Southend have been backed in from a high of 6.411/2 to their current price of 4.77/2 to beat Hull on Saturday afternoon at Roots Hall.
4.77/2 presents excellent value for a team at home who've lost just one of their last ten league games playing a side that will probably rest players and will hardly be prioritising this competition. What's more, the Shrimpers have the second best defensive record in their division and concede, on average, less than a goal a game.
Add the fact that Hull face a crucial game with Crystal Palace in the Premier League just three days later into the mix, and that Hull struggle to score goals at the best of times, and you have all the elements for an upset.
Value Hunter Recommended Bets
Back Bournemouth to beat Liverpool at 9.08/1
Back Southend to beat Hull at 4.77/2