The headline act promises to be a fascinating fight but punters searching for value will find plenty to get excited about on a stacked undercard. Betfair's boxing writer Frankie Monkhouse gives his views...
"Back Mendy to continue his winning ways at a cracking [4.1]. He should never be as big as that"
The focus of attention is on world heavyweight champion Anthony Joshua as he battles Russian challenger Alexander Povetkin at Wembley Stadium on Saturday night and you can read our big fight preview here.
As well as the main event, Matchroom Sport have also put together a fascinating undercard with Luke Campbell, David Price and Matty Askin all on the bill and hoping to steal the limelight.
The odds on another AJ win are tight, as you would expect given the 6ft 6inch Londoner's form so far, but there's plenty in the specials and more than enough value to be had from the supporting acts to ensure it'll be an enjoyable round for punters.
Let's pick through the highlights...
David Price v Sergey Kuzmin
It came as a bit of a shock to many followers of the heavyweight division to learn David Price would continue fighting following that brutal KO defeat at the hands of Povetkin in Cardiff last time. Yes, the victor went on to challenge for a world title and Price was in the contest until being chopped down by a savage right hand, but he has now lost five of 27 with each of those defeats coming inside the distance.
That's worrying when sharing a ring with 31-year-old Russian Sergey Kuzmin, a man who is undefeated from a dozen outings and has stopped nine of the men placed in front of him so far. Saturday represents a step up in class for the 6ft 4inch Saint Petersburg resident but it's also a real chance for him to launch his career, knowing an impressive win here would catapult him towards the big money fights.
Kuzmin is favourite with [1.22] available on the Betfair Exchange, against the [4.5] of his British opponent. The Method of victory market and a KO/TKO cheer for the jolly should oblige, but at 3/10 to back on the Betfair Sportsbook this is probably one for your acca rather than a standalone bet.
Luke Campbell v Yvan Mendy
A chance for Hull's Luke Campbell to avenge one of the two defeats on his record. The 30-year-old lightweight lost to Frenchman Mendy back in late 2015 by a split decision and it was an outing that would've taught the southpaw much about professional boxing. Win that and he would've been well-placed to challenge for world honours, the defeat sending him back through the pack.
Since that reverse Campbell has fought seven times, winning six and losing to Jorge Linares by another split decision. Five of the victories in that run have come early but this bout is expected to travel the distance. Following their first meeting Mendy has won seven on the bounce, four on points. The 33-year-old travels from his Oise base on the back of a 10-fight winning run and that shouldn't be overlooked.
This is a tough one to call and we wouldn't blame anyone for sitting on the fence and backing a draw at [25.0] on the Exchange. The scorecards last time had no more than three rounds between the rivals and that was with Campbell receiving a count in the fifth. Take that away and it would've been tighter still. Now consider the fact Luke has improved since then and we have a fight on our hands.
This bout to travel the 12-round distance is a 2/5 shot on the Sportsbook and that may appeal to accumulator backers. Campbell finds himself a [1.31] fav but in such a close contest it's always worth taking a shot at the value. Back Mendy to continue his winning ways at a cracking [4.1]. He should never be as big as that.
Lawrence Okolie v Matty Askin
Hackney cruiserweight Lawrence Okolie is picked to take his undefeated record into double-figures when sharing a ring with the experienced Matty Askin who will be taking part in his 28th paid bout.
6ft 5inch Okolie has dealt with the nine men placed in front of him to date, stopping seven, but he'll get nothing for free against The Assassin who is undefeated since dropping a majority decision to Ovill McKenzie in 2015.
Blackpool's Askin will know more than enough to ensure this British title fight goes into the second half but a punt on Okolie to win on points looks the shrewd play here.
Followers will be more than happy with the 11/4 up for grabs, market best price when playing through the Sportsbook. Keep your stakes to interest level on that one.
Yvan Mendy win @ [4.1] (Betfair Exchange)
Lawrence Okolie on points @ 11/4 (Betfair Sportsbook)